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ARTICLE siRNA silencing of angiotensin converting enzyme 2 reduced severe acute respiratory syndrome associated coronavirus replications in Vero E6 cells C Y Lu collection analysis and interpretation of data the writing of the report and the decision to submit the paper for publication Conflictofintereststatement Allauthorsdeclarenoconflictofinterest References 1 Groneberg DA Poutanen SM Low DE Lode H Welte T Zabel P 2005 Treatment and vaccines for severe acute respiratory syndrome Lancet Infect Dis 5 147 155 2 Hsueh PR Hsiao CH Yeh SH et al 2003 Microbiologic characteristics serologic responses and clinical manifestations in severe acute respiratory syndrome Taiwan Emerg Infect Dis 9 1163 1167 3 Gallagher TM Buchmeier MJ 2001 Coronavirus spike proteins in viral entry and pathogenesis Virology 279 371 374 4 Li W Moore MJ Vasilieva N et al 2003 Angiotensin converting enzyme 2 is a functional receptor for the SARS coronavirus Nature 426 450 454 5 Donoghue M Hsieh F Baronas E et al 2000 A novel angiotensin converting enzyme related carboxypeptidase ACE2 converts angiotensin I to angiotensin 1 9 Circ Res 87 E1 E9 6 Harmer D Gilbert M Borman R Clark KL 2002 Quantitative mRNA expression profiling of ACE 2 a novel homologue of angiotensin converting enzyme FEBS Lett 532 107 110 7 Agrawal N Dasaradhi PV Mohmmed A Malhotra P Bhatnagar RK Mukherjee SK 2003 RNA interference biology mecha nism and applications Microbiol Mol Biol Rev 67 657 685 8 Fire A Xu S Montgomery MK Kostas SA Driver SE Mello CC 1998 Potent and specific genetic interference by double stranded RNA in Caenorhabditis elegans Nature 391 806 811 9 Voinnet O 2005 Induction and suppression of RNA silencing insights from viral infections Nat Rev Genet 6 206 220 10 Ksiazek TG Erdman D Goldsmith CS et al 2003 A novel coronavirus associated with severe acute respiratory syndrome N Engl J Med 348 1953 1966 11 Drosten C Gunther S Preiser W et al 2003 Identification of a novel coronavirus in patients with severe acute respiratory syndrome N Engl J Med 348 1967 1976 12 Li T Zhang Y Fu L et al 2005 siRNA targeting the leader sequence of SARS CoV inhibits virus replication Gene Ther 12 751 761 13 Qin ZL Zhao P Zhang XL et al 2004 Silencing of SARS CoV spike gene by small interfering RNA in HEK 293Tcells Biochem Biophys Res Commun 324 1186 1193 14 Zhang Y Li T Fu L et al 2004 Silencing SARS CoV Spike protein expression in cultured cells by RNA interference FEBS Lett 560 141 146 15 Shi Y Yang DH Xiong J Jia J Huang B Jin YX 2005 Inhibition of genes expression of SARS coronavirus by synthetic small interfering RNAs Cell Res 15 193 200 16 Qin ZL Zhao P Cao MM Qi ZT 2007 siRNAs targeting terminal sequences of the SARS associated coronavirus mem brane gene inhibit M protein expression through degradation of M mRNA J Virol Methods 145 146 154 17 Wang Z Ren L Zhao X et al 2004 Inhibition of severe acute respiratory syndrome virus replication by small interfering RNAs in mammalian cells J Virol 78 7523 7527 18 Ni B Shi X Li Y Gao W Wang X Wu Y 2005 Inhibition of replication and infection of severe acute respiratory syndrome associated coronavirus with plasmid mediated interference RNA Antivir Ther 10 527 533 19 Akerstrom S Mirazimi A Tan YJ 2007 Inhibition of SARS CoV replication cycle by small interference RNAs silencing specific SARS proteins 7a 7b 3a 3b and S Antiviral Res 73 219 227 20 Wu CJ Huang HW Liu CY Hong CF Chan YL 2005 Inhibition of SARS CoV replication by siRNA Antiviral Res 65 45 48 21 Li BJ Tang Q Cheng D et al 2005 Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque Nat Med 11 944 951 22 Wu CJ Chan YL 2006 Antiviral applications of RNAi for coronavirus Expert Opin Investig Drugs 15 89 97 23 Chang Z Babiuk LA Hu J 2007 Therapeutic and prophylactic potential of small interfering RNAs against severe acute respira tory syndrome progress to date BioDrugs 21 9 15 24 Anderson J Akkina R 2005 CXCR4 and CCR5 shRNA transgenic CD34 cell derived macrophages are functionally normal and resist HIV 1 infection Retrovirology 2 53 25 Novina CD Murray MF Dykxhoorn DM et al 2002 siRNA directed inhibition of HIV 1 infection Nat Med 8 681 686 26 Hattermann K Muller MA Nitsche A Wendt S Donoso Mantke O Niedrig M 2005 Susceptibility of different eukaryotic cell lines to SARS coronavirus Arch Virol 150 1023 1031 27 Hofmann H Geier M Marzi A et al 2004 Susceptibility to SARS coronavirus S protein driven infection correlates with expression of angiotensin converting enzyme 2 and infection can be blocked by soluble receptor Biochem Biophys Res Commun 319 1216 1221 28 Nie Y Wang P Shi X et al 2004 Highly infectious SARS CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression Biochem Biophys Res Commun 321 994 1000 29 Mossel EC Huang C Narayanan K Makino S Tesh RB Peters CJ 2005 Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication J Virol 79 3846 3850 30 Jeffers SA Tusell SM Gillim Ross L et al 2004 CD209L L SIGN is a receptor for severe acute respiratory syndrome coronavirus Proc Natl Acad Sci USA 101 15748 15753 714 Eur J Clin Microbiol Infect Dis 2008 27 709 715 31 He ML Zheng BJ Chen Y et al 2006 Kinetics and synergistic effects of siRNAs targeting structural and replicase genes of SARS associated coronavirus FEBS Lett 580 2414 2420 32 deLangA OsterhausAD HaagmansBL 2006 Interferon gamma and interleukin 4 downregulate expression of the SARS coronavi rus receptor ACE2 in Vero E6 cells Virology 353 474 481 33 Goulter AB Goddard MJ Allen JC Clark KL 2004 ACE2 gene expression is up regulated in the human failing heart BMC Med 2 19 34 Crackower MA Sarao R Oudit GY et al 2002 Angiotensin converting enzyme 2 is an essential regulator of heart function Nature 417 822 828 Eur J Clin Microbiol Infect Dis 2008 27 709 715 715